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OCR: ed to that The term localised myxoedema is prefer tion may of 'pretibial myxoedema' since the condi on local affect other parts of the body, depending al forms: a pressure or trauma. It may occur in seve osum nodular form, mimicking erythema nod h); a (which differs by being tender to the tou edema, sheet-like form with largely nonpitting ceous coarse thickening of the skin, a red-viola ny form discoloration, and coarse hairs; and a ho taneous with gross overgrowth of skin and subcu (Fig. 17.41) .tissue on the dorsum of the feet and toes by a ery high The affected areas are densely infiltrated hyaline mucopolysaccharide material. V e usually circulating levels of TSH-R antibodies a dema. present in patients with localised myxoe